The Green Bay Packers are overseas for their first ever international regular season game, as they take on the New York Giants in London.

In the first ever NFL UK game between two winning teams, the Packers will come in as heavy favourites over the Giants, who have started the season surprisingly well under new head coach Brian Daboll.

Here are five things to watch as the Packers face the Giants at Tottenham Hotspur Stadium.

Stop the run… but seriously this time

After putting his injury woes in the rear-view mirror, Saquon Barkley looks his old self again, and leads the NFL in rushing through four weeks.

It’s no exaggeration to say Barkley is the main reason the Giants are 3-1, and stopping the former Penn State running back has to be the Packers’ top priority.

Green Bay’s run defense has been suspect in the early season, and whether the blame rests on Joe Barry’s play-calling or a lack of execution by the players, the Packers will have to step things up on Sunday to keep Barkley in check.

Simply put, if the Giants can’t run the ball effectively, they can’t win this game. A great deal of focus will be on Barry’s defense and how they adjust after allowing Damien Harris and Rhamondre Stevenson to keep the Patriots in the game last week.

How healthy is Daniel Jones?

Jones had no injury designation on New York’s final injury report, meaning he’ll play on Sunday.

With backup QB Tyrod Taylor dealing with a concussion, he kind of had to give it a go this week unless he was completely compromised, but the unknown factor surrounding Jones is whether or not his mobility will be impacted by his ankle injury.

The former first-rounder relies heavily on his ability to move in order to have success, and if he is reduced to a pocket passer, the Packers defense will be licking its chops.

Will AJ Dillon get going?

The Packers have the luxury of possessing two top running backs, which allows them to balance out the workload. That will be just as important as Green Bay’s players battle jetlag this week.

Dillon has carried the ball nine more times than Aaron Jones this season, but has been less effective, with an average of 3.7 yards per rush and a long of just 14 yards.

It feels like Dillon has been close to breaking a big run on multiple occasions, so it may just be a matter of time before Quadzilla gets warmed up. Can he make his mark in London?

Will there be changes to Green Bay’s offensive line?

It’s obvious Elgton Jenkins has struggled at right tackle so far this season, but it’s tough to tell whether this is a result of him working back to his full form after the ACL injury, him just not being suited to the position, or a bit of both.

Yosh Nijman may be a more natural tackle than Jenkins, but the Packers have been reluctant to try him on the right side.

While the Packers are clearly still searching for their ‘best five’, they may choose to stick with the status quo in an unusual week. However, Matt LaFleur at least admitted they have considered making a change along the O-line.

The London atmosphere

Packers fans in Europe have waited a long time to get the chance to see their team play in person, and with plenty of fans also coming over from the US, there’s a chance this resembles a true Packers home game rather than a neutral site matchup.

If that is the case, Green Bay will have a significant advantage on Sunday. Here’s hoping the British fans know not to do the wave while the Packers are on offense.